Thesis
Automate AI research
Y CombinatorFall 2025ActiveB2BAI
What they do
Problem
AI research and model discovery are slow, manual, and hard to scale systematically.
Solution
Thesis provides an autonomous AI research lab that automates and scales the process of designing, training, and evaluating machine learning models as an intelligent search problem.
Who it's for
AI researchers and machine learning teams at labs and companies building new models and breakthroughs.
Founders
Sergio Charles
Co-Founder & CEO
Thesis will automate AI research. Prev: AI R&D at Google X, Nvidia and Stanford's AI Lab, working with Andrew Ng and Chelsea Finn. Stanford B.S. Math & CS, M.S. Stats
Luigi Charles
Founder
Betting the farm that AI will become meaningful in the discovery of new science. Second time founder. Previously scaled stablecoin payments infrastructure from zero to billions. Columbia CS & Math.
Open roles 1
Member of Technical Staff
Company timeline
- Founded2025
- YC batchFall 2025
- StatusActive
- Team size2 people
- LocationSan Francisco, CA, USA
