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Shasqi

Targeting Cancer with Click Chemistry

Y CombinatorWinter 2015ActiveHealthcareDrug Discovery and DeliveryBiotechTherapeutics

What they do

Problem

Systemic cancer therapies often cause dose-limiting toxicity because they expose the whole body to powerful drugs instead of concentrating treatment at tumors.

Solution

The CAPAC™ click-chemistry platform localizes a reagent at the tumor to activate a systemically delivered protodrug only at the tumor site for targeted therapy with reduced systemic exposure.

Who it's for

Oncologists and cancer treatment centers that administer therapeutic drugs to patients.

Founders

Jose M. Mejia Oneto
Founder/CEO

José M Mejía Oneto is a physician scientist with training in Organic Chemistry at Emory and Orthopedics at UC Davis. During his clinical training, Jose recognized the need for a better way to get drugs to the right location in the body. Joined the YC program in 2015 with Tambo and in 2018 its spinoff Shasqi, focussing on pioneering click chemistry in humans for better cancer drugs. Shasqi has raised a more than $60M in funding, with its lead asset in Phase 2 and a growing pipeline of drugs.

Company timeline

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