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SFA Therapeutics

Regulating the immune system to block cancer & autoimmune diseases

Y CombinatorSummer 2021ActiveHealthcareTherapeuticsAI-powered Drug DiscoveryAnti-AgingBiotechHealth & Wellness

What they do

Problem

Autoimmune diseases and inflammation-driven cancers lack safe, effective treatments that address the underlying immune dysregulation driving chronic inflammation.

Solution

SFA Therapeutics develops therapeutically tailored oral small-molecule drugs that regulate the immune system to block chronic inflammation in autoimmune diseases and certain cancers.

Who it's for

Patients with autoimmune diseases and inflammation-driven cancers treated via prescribing clinicians and healthcare systems.

Founders

Ira Spector
Founder

Dr. Spector is the co-founder of SFA, a microbiome-derived pharmaceutical company focused on new advancements in the treatment inflammatory diseases. An experienced drug developer with over 30 years of experience, he helped develop 34 drugs and 12 medical devices, including Enbrel, Effexor, Protonix, Prevenar, Ozurdex, Botox for Overactive Bladder, Chronic Migraine and Cerebral Palsy. He holds BS degrees in Physics and EE from Washington University, an MBA from Drexel, and a PhD from Rutgers.

Alla Arzumanyan
Founder

MS is Microbiology, PhD in Biotechnology, Assistant Professor at Temple University, Co-Founder and Co-Inventor at SFA Therapeutics, Inc. Performed a case-control, Proof-of-Activity Human study to evaluate treatment effect of SFA002 drug (proprietary of SFA Therapeutics, Inc.) on patients with plaque psoriasis. Worked with Axella Research on pre-IND application for SFA002. Worked with HEC (Sunshine Lake Pharma Co., China), Theravectys, and ThirdLaw LLC (still collaborating with the latter)

Mark Feitelson
Founder

Mark Feitelson received his Ph.D. in Microbiology/Immunology from UCLA. He began his work with hepatitis B at Stanford University, and was then recruited to the Fox Chase Cancer Center by Dr. Baruch Blumberg (Nobel laureate). In 1991, Dr. Feitelson moved to Thomas Jefferson University, and in 2007, to Temple University as a Professor of Biology. His work has been supported by NIH, industry and foundations. He has more than 150 publications and 180 abstracts. He is also CSO of SFA Therapeutics.

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