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Gilgamesh Pharmaceuticals

Gilgamesh Pharmaceuticals, a Clinical stage biotechnology company…

Y CombinatorSummer 2020ActiveHealthcareDrug Discovery and DeliveryTherapeuticsPsychedelicsMental Health

What they do

Problem

Many mental health conditions lack safe and effective treatment options that address underlying neurobiology.

Solution

The company develops novel new chemical entity drug candidates for mental health disorders using medicinal chemistry, neuroscience, and drug development expertise.

Who it's for

Pharmaceutical partners, clinicians, and patients who need new therapeutics for mental health disorders.

Founders

JONATHAN SPORN
Founder

Duke University BS, MD from University of Miami, former Chief of Psychiatry in Boston Area. Academic work at Mass General Hospital and NIH (intramural), researcher at JNJ in psychiatry and neurology, and then at Pfizer Inc in NYC (Clinical Disease Area Expert in Neuroscience Area), Founder of start up, Perception Neuroscience (exited) and was CSO, and now Founder of Gilgamesh. Live in NYC and mountains of NC. Assistant Professor of Psychiatry and Exp Therapeutics at Columbia University

Andrew Kruegel
Founder

I am a medicinal chemist, pharmacologist, and entrepreneur with extensive experience in the design and preclinical development of psychoactive drugs for the future treatment of psychiatric illnesses. In the context of my entrepreneurial endeavors I have also built significant expertise in business, fundraising, operations, and intellectual property strategy.

Dalibor Sames
Founder

Professor of Chemistry at Columbia University with expertise in synthetic chemistry, medicinal chemistry, molecular design, synaptic imaging, neuropharmacology, and experimental therapeutics. Led new conceptual advances in chemical synthesis (C-H bond functionalization), developed fluorescent false neurotransmitters (FFNs), elucidated the mechanism of action of antidepressant tianeptine, expertise in iboga alkaloid and mitragynines chemistry and pharmacology.

Company timeline

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